The axons are unmyelinated in the retina and on the papillary surface, but become myelinated at the posterior end of the optic nerve head as they pass through one of 200 to 300 holes in the lamina cribrosa. Myelin in the optic nerve is CNS myelin, formed by oligodendroglia. Loss of axons and other abnormalities involving the NFLcan sometimes be appreciated ophthalmoscopically. “sieve”), the collagenous support of the optic disc. Here incidence of papillitis is more or equal to that of retrobulbar optic neuritis, visual recovery is poor, causes being more of infectious or idiopathic and less recurrence rate.The retinal ganglion cell axons form the retinal nerve fiber layer (NFL) as they stream toward the disc to exit through the lamina cribrosa (L. CONCLUSIONS In Indian scenario the profile of optic neuritis is different.
One case on follow up was eventually diagnosed as multiple sclerosis. Demyelinating lesions in the brain were present in 2 patients, one of which was already diagnosed as MS. Colour vision recovery was noted in 39.86 %. Approximately 64.68 % of eyes retained VA of or 6/18 or more. Baseline median logMAR visual acuity (VA) was 1.17 0.8, which improved to 1.6 0.6, within one week and 0.79 +/- 0.6 within one month improving to 0.55 +/- 0.6 in three months. All patients complained of DOV but pain on ocular movements were complained by 36.66 % patients. Bilateral presentation was seen in 23.33 % cases. Retrobulbar neuritis (56.7 % of eyes) was more common than papillitis (43.33 % of eyes) but papillitis was a more common presentation in males (73.7 %). Female preponderance was seen (63.33 % of cases). They were followed up and visual parameters were assessed and thus clinical profiling and visual outcomes were done. Thirty patients were included in the study. METHODS It was a prospective study done for a duration of 10.8 +/- 8.4 months in which all patients clinically diagnosed with optic neuritis were studied. We wanted to evaluate the clinical profile and visual outcome of optic neuritis in India. But the trend of optic neuritis in India is very different and not many studies have been conducted to know about this disease and its causes in this geographical region.
Early identification and early management have shown promises in reducing ocular morbidity as well as neurological morbidity and recurrences. Multiple sclerosis is one of the major causes of disability disease in US and one of the most common early manifestations is optic neuritis. When it comes to optic neuritis the pattern in developing countries is different than developed countries.
The causes of blindness, natural history differs between western countries and India. Abstract : BACKGROUND Blindness is a major health problem worldwide and India has been an epicenter in the number of blindness cases.
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